GeneTex
  • Country / Location Selection

United States (US)

uPAR antibody [18L1]

Cat No. GTX53052

Host

Mouse

Clonality

Monoclonal

Clone Name

18L1

Isotype

IgG1

Application

WB, FACS, Neutralizing/Inhibition

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
FACS 1:50 - 1:100
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant uPAR EC domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD87 , PLAUR , UPAR , URKR , plasminogen activator, urokinase receptor , uPA Receptor , uPAR

Cellular Localization

Cell membrane,Cell projection,Invadopodium membrane,Secreted

Background

This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

There are currently no references for uPAR antibody [18L1] (GTX53052). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for uPAR antibody [18L1] (GTX53052). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 329