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EDG1 antibody

Anti-EDG1 antibody used in IHC (Paraffin sections) (IHC-P). GTX77919
Anti-EDG1 antibody used in IHC (Paraffin sections) (IHC-P). GTX77919

Cat. No. GTX77919

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
25 μg ($399)
See all EDG1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P 3 - 6 μg/ml
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Predict Reactivity

Mouse, Rat, Zebrafish, Bovine, Cat, Dog, Hamster, Pig, Monkey, Bat, Elephant, Gibbon, Gorilla, Horse, Lizard, Marmoset, Opossum, Orangutan, Panda, Shrew, Turkey, Xenopus, Platypus(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human S1PR1 / EDG1.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_424867

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sphingosine-1-phosphate receptor 1 , CD363 , CHEDG1 , D1S3362 , ECGF1 , EDG1 , S1P1 , S1PR1 , sphingosine1phosphate receptor 1

Cellular Localization

Cell membrane,Endosome,Membrane raft

Background

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Database

Research Area

DATA IMAGES

Anti-EDG1 antibody used in IHC (Paraffin sections) (IHC-P). GTX77919

GTX77919 IHC-P Image

IHC-P analysis of human, vascular endothelium tissue using GTX77919 EDG1 antibody.

Anti-EDG1 antibody used in IHC (Paraffin sections) (IHC-P). GTX77919

GTX77919 IHC-P Image

IHC-P analysis of human, placenta tissue using GTX77919 EDG1 antibody.

REFERENCE

Application Reference

Mourad-Zeidan AA et al. Am J Pathol 2008; 173 (6) : 1839-52 Expression profiling of Galectin-3-depleted melanoma cells reveals its major role in melanoma cell plasticity and vasculogenic mimicry.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399