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S100 beta antibody

Anti-S100 beta antibody used in IHC (Paraffin sections) (IHC-P). GTX14688
Anti-S100 beta antibody used in IHC (Paraffin sections) (IHC-P). GTX14688
Anti-S100 beta antibody used in Western Blot (WB). GTX14688

Cat. No. GTX14688

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IP, ELISA, IHC

Reactivity

 Human, Mouse, Rat, Baboon
Package
100 μg ($429)
See all S100 beta products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500
ICC/IF Assay dependent
IHC-P Assay dependent
IP Assay dependent
ELISA 1:10000
IHC Assay dependent
Not tested in other applications.

Calculated MW

11 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine, 0.5% BSA, 30% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.65 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length protein of human S100 beta/beta homodimer.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_372450

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

S100 calcium binding protein B , NEF , S100 , S100-B , S100beta

Cellular Localization

Cytoplasm , Nucleus

Background

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-S100 beta antibody used in IHC (Paraffin sections) (IHC-P). GTX14688

GTX14688 IHC-P Image

IHC-P analysis of baboon brain tissue using GTX14688 S100 beta antibody.
Dilution : 1:50

Anti-S100 beta antibody used in IHC (Paraffin sections) (IHC-P). GTX14688

GTX14688 IHC-P Image

IHC-P analysis of rat testis tissue using GTX14688 S100 beta antibody.
Dilution : 1:50

Anti-S100 beta antibody used in Western Blot (WB). GTX14688

GTX14688 WB Image

WB analysis of S100 beta recombinant protein using GTX14688 S100 beta antibody.
Dilution : 1:500

REFERENCE

Application Reference

Birbrair A et al. PLoS One 2011; 6 (2) : e16816 Nestin-GFP transgene reveals neural precursor cells in adult skeletal muscle.
Application : ICC/IF
Reactivity : Mouse
Li YF et al. J Neurosci 2011; 31 (1) : 172-83 Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling.
Application : IHC
Reactivity : Mouse
Li YF et al. Neuropsychopharmacology 2009; 34 (11) : 2404-19 Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 inhibitor rolipram on behavior depend on cyclic AMP response element binding protein-mediated neurogenesis in the hippocampus.
Application : IHC
Reactivity : Mouse
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Package List Price ($)
$ 429