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PBR antibody, C-term

Anti-PBR antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89258
Anti-PBR antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89258
Anti-PBR antibody, C-term used in Western Blot (WB). GTX89258

Cat. No. GTX89258

Reference 1

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all PBR products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.3μg/ml
IHC-P 5μg/ml

Note :

IHC-P
Human Colon shows strong cytoplasm staining of absorptive cells.
Not tested in other applications.

Calculated MW

11 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89258-PEP).

Product Note

This antibody is expected to recognise one isoform (NP_000705.2) only.

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-RDNHGWRGGRRLPE, from the C Terminus of the protein sequence according to NP_000705.2.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

RRID

AB_10726223

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Translocator Protein , Bpbs , Bzrp , Dbi , Ibp , Mbr , Pbr , Pbs , Pkbs , Ptbr , Mdrc , Pk18 , Tspo

Background

Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012]

Research Area

DATA IMAGES

Anti-PBR antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89258

GTX89258 IHC-P Image

IHC-P analysis of human colon using GTX89258 PBR antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 2.5μg/ml

Anti-PBR antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89258

GTX89258 IHC-P Image

IHC-P analysis of human kidney using GTX89258 PBR antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 5μg/ml

Anti-PBR antibody, C-term used in Western Blot (WB). GTX89258

GTX89258 WB Image

WB analysis of human breast cancer lysate using GTX89258 PBR antibody, C-term.
Dilution : 0.1μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

Application Reference

Su Z et al. Eur J Nucl Med Mol Imaging 2013; 40 (9) : 1406-19 [11C]-(R)PK11195 tracer kinetics in the brain of glioma patients and a comparison of two referencing approaches.
Application : IHC-P
Reactivity : Human
Submit a Reference

REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399