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Summary The antibody blocks cell surface IGF-I R mediated IGF-I and IGF-II biological activity. At optimal antibody concentration, no more than 40-60% of the IGF-I or IGF-II activity can be blocked by this antibody.

Summary Recognizes a (Mr 156 kDa) cell surface glycoprotein expressed on virtually all peripheral bloodgranulocytes.(1,2,3) The CD15 antigen is expressed on approximately 95% of human peripheral bloodeosinophils and neutrophils and is present on approximately 20% of mature circulating monocytes. Anti-CD15 has virtually no reactivity with T or B cells.(1,2,3)

Summary fibrinogen and fibrin degradation products.

Summary Not cross-reacting with transferrin.

Summary Epitope specificity : a.a.r. 21-40