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Summary Human Prostate Specific Antigen (PSA). PSA is a tumor-associated antigen with a molecular weight of 34kDa. The antigen is found in normal prostatic epithelial lining cells of the ducts and acini, as well as inprimary and metastatic prostate carcinoma cells. PSA reactivity may also be found in BPH (benignprostatic hypertrophy), though the pattern of staining is different than that found in carcinoma tissues. Thestaining pattern ranges from cytoplasmic and secretory in normal and benign prostate to cytoplasmic withmembrane in neoplastic prostate.

Summary Reacts with total PSA (free PSA and PSA complexed with ACT).

Summary Reacts with residues 262-277 [IRKYETQQQKWLKGPQ] of the human Kallikrein 13 protein.

Summary This antibody recognizes the following strains of mice: C57BL/6, C57BL/10, C57/L, C58A, AKR, 129, SJL, NZB, C3H, CE, CBA/H.

Summary Recognises Plasminogen/Plasmin