Normal Tissue Gallery- GTX648264

Rad51 antibody [HMV4727] HistoMAX™

 

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Adrenal gland

Aorta, endothelium

Appendix, mucosa – Moderate to strong nuclear Rad51 staining of fraction of crypt cells and of a large fraction of germinal centre cells.

Appendix, muscular wall

       

Bone marrow – Moderate to strong nuclear Rad51 staining of a large fraction of hematopoietic cells.

Breast

Bronchus, mucosa – Weak nuclear Rad51 positivity of a very small subset of respiratory epithelial cells.

Cerebellum (molecular layer, Purkinje cell layer, granule cell layer)

       

Cerebellum (white matter)

Cerebrum (grey matter)

Cerebrum (white matter)

Colon descendens, mucosa – Weak to moderate nuclear Rad51 staining of a fraction of crypt cells.

       

Colon descendens, muscular wall

Duodenum, Brunner gland

Duodenum, Mucosa – Distinct nuclear Rad51 staining of a fraction of crypt cells of the mucosa. The surface epithelium and the tufts are largely Rad51 negative.

Epididymis (Caput)

       

Esophagus, muscular wall

Esophagus, squamous epithelium – Strong nuclear Rad51 staining of a subset of suprabasal squamous epithelial cells.

Fallopian tube, mucosa

Fat

       

Gallbladder, epithelium

Heart muscle

Ileum, mucosa – Distinct nuclear Rad51 staining of fraction of crypt cells of the mucosa. The surface epithelium and the tufts are largely Rad51 negative.

Ileum, muscular wall

       

Kidney, cortex

Kidney, medulla – Distinct nuclear Rad51 positivity of very small fraction of cells (_1_) in this sample.

Kidney, pelvis, muscular wall

Kidney, pelvis, urothelium – Weak to moderate nuclear Rad51 staining of few scattered urothelial cells.

       

Liver – The liver is largely Rad51 negative but there is a distinct nuclear Rad51 positivity of a very small fraction of cells (_1_).

Lung

Lymph node – Moderate to strong nuclear Rad51 staining of a large fraction of germinal centre cells.

Ovary, corpus luteum – Distinct nuclear Rad51 positivity of small fraction of corpus luteum cells (_5_).

       

Ovary, follicular cyst – Moderate to strong nuclear Rad51 positivity of a fraction of granulosa and theca cells (_5_). Scattered Rad51 positive cells in the adjacent ovarian stroma.

Ovary, stroma

Pancreas – The pancreas is largely Rad51 negative but there is a distinct nuclear Rad51 positivity of a very small fraction of cells (_1_).

Parathyroid gland

       

Parotid gland

Pituitary gland, anterior lobe

Pituitary gland, posterior lobe

Placenta (amnion)

       

Placenta (chorion) – Strong nuclear Rad51 staining of a very small fraction of chorion cells.

Placenta, early

Placenta, mature – Strong nuclear Rad51 staining of a fraction of syncytiotrophoblast cells.

Prostate

       

Rectum, mucosa – Strong nuclear Rad51 staining of a fraction of crypt cells.

Seminal vesicle

Sinus paranasales – Distinct nuclear Rad51 positivity of a small subset of respiratory epithelial cells.

Skeletal muscle

       

Skin – Strong nuclear Rad51 staining of the basal cell layer.

Skin, hairfollicel and sebaceous glands – Some basal cells of hair follicles show a distinct nuclear Rad51 positivity.

Spleen – Moderate to strong nuclear Rad51 staining of a fraction of cells, mainly in the white pulp.

Stomach, antrum – Distinct nuclear Rad51 staining in a fraction of neck cells of the mucosa. Gastric glands are largely Rad51 negative.

       

Stomach, antrum – Gastric glands are largely Rad51 negative

Stomach, corpus – Gastric glands are largely Rad51 negative

Stomach, muscular wall

Sublingual gland

       

Submandibular gland

Testis – Nuclear Rad51 positivity of variable intensity (weak to strong) of a large fraction of maturing germ cells. Spermatids and Sertoli cells are Rad51 negative.

Thymus – Moderate to strong nuclear Rad51 staining of a considerable fraction of cortical cells, while the fraction of positive cells is low in the medulla.

Thymus – Moderate to strong nuclear Rad51 staining of a large fraction of cortical cells, while the fracrion of positive cells is low in the medulla.

       

Thyroid gland

Tonsil – Moderate to strong, predominantly nuclear Rad51 staining of a large fraction of germinal centre cells.

Urinary bladder, muscular wall

Urinary bladder, urothelium – Weak to moderate nuclear Rad51 staining of few scattered urothelial cells.

       

Uterus, ectocervix – Strong nuclear Rad51 staining of a thin suprabasal cell layer.

Uterus, endocervix

Uterus, endometrium (pregnancy)

Uterus, endometrium (proliferation) – Moderate to strong nuclear Rad51 staining in a large fraction of endometrium gland cells in this sample.

       

Uterus, endometrium (secretion) – Absence of endometrium gland staining in this sample.

Uterus, myometrium

   

 

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