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Apolipoprotein B ELISA pair [LDL20/17/LDL11]

Apolipoprotein B ELISA pair [LDL20/17/LDL11]. GTX03048

Cat. No. GTX03048

Application

ELISA, Sandwich ELISA

Reactivity

Human
Package
1 pair ($659)
PRODUCT

Product Content

GTX02900-02
Type : Detection antibody
Host : Mouse
Conjugation : Biotin
Package : 250 μg
GTX02901
Type : Capture antibody
Host : Mouse
Conjugation : Unconjugated
Package : 250 μg

APPLICATION

PROPERTIES

Form

Liquid

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

apolipoprotein B , FLDB , LDLCQ4 , apoB-100 , apoB-48

Cellular Localization

Cytoplasm , Secreted

Background

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Apolipoprotein B ELISA pair [LDL20/17/LDL11]. GTX03048

GTX03048 ELISA Image

Sandwich ELISA analysis of human apoB protein using GTX02901 Apolipoprotein B antibody [LDL20 + LDL17] as coating antibody and GTX02900-02 Apolipoprotein B antibody [LDL11] (Biotin) as detecting antibody.
Substrate : pNPP

REFERENCE

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REVIEW

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Package List Price ($)
$ 659