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CD3 epsilon antibody [MSVA-003R] HistoMAX

Anti-CD3 epsilon antibody [MSVA-003R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04389
Anti-CD3 epsilon antibody [MSVA-003R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04389
Anti-CD3 epsilon antibody [MSVA-003R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04389

Cat. No. GTX04389

Host

Rabbit

Clonality

Monoclonal

Clone Name

MSVA-003R

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
500 μl ($679)
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48 and BOND RX - Leica. The detailed steps by Autostainer please refer to the protocol.

Not tested in other applications.

Calculated MW

23 kDa. ( Note )

Positive Control

Tonsil: A moderate to strong membranous staining should be seen in all T-cells in the interfollicular T-zones and in the germinal centres (few cells).

Negative Control

Tonsil: All epithelial structures and B-cells should not show any CD3 immunostaining.

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide from human CD3e protein (around aa 20-40)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD3e molecule , IMD18 , T3E , TCRE

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD3 epsilon antibody [MSVA-003R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04389

GTX04389 IHC-P Image

IHC-P analysis of human squamous cell carcinoma tissue section using GTX04389 CD3 epsilon antibody [MSVA-003R] HistoMAX.
Squamous cell carcinoma containing numerous CD3 epsilon positive T lymphocytes.

Anti-CD3 epsilon antibody [MSVA-003R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04389

GTX04389 IHC-P Image

IHC-P analysis of human appendix mucosa tissue section using GTX04389 CD3 epsilon antibody [MSVA-003R] HistoMAX.
In the appendix numerous CD3 epsilon positive T lymphocytes occur in the epithelium the lamina propria and in germinal centres.

Anti-CD3 epsilon antibody [MSVA-003R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04389

GTX04389 IHC-P Image

IHC-P analysis of human diffuse large B-cell lymphoma tissue section using GTX04389 CD3 epsilon antibody [MSVA-003R] HistoMAX.
Diffuse large B cell lymphoma infiltrated by numerous CD3 epsilon positive non neoplastic lymphocytes.

REFERENCE

There are currently no references for CD3 epsilon antibody [MSVA-003R] HistoMAX (GTX04389). Be the first to share your publications with this product.

REVIEW

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Package List Price ($)
$ 679