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CD8 alpha antibody [MSVA-008R] HistoMAX™

Comparison HistoMAX
Anti-CD8 alpha antibody [MSVA-008R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04391
Anti-CD8 alpha antibody [MSVA-008R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04391
Anti-CD8 alpha antibody [MSVA-008R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04391

Cat. No. GTX04391

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 MSVA-008R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($679),
100 μl ($299)
See all CD8 alpha products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

Positive Control

Tonsil (interfollicular areas)

Negative Control

Epithelial tissues, majority of cells in germinal centres of lymphatic organs

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to residues within aa135-235 of CD8 alpha.

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD8a molecule , CD8 , Leu2 , p32

Cellular Localization

Cell membrane , Secreted

Background

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Database

Research Area

DATA IMAGES

Anti-CD8 alpha antibody [MSVA-008R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04391

GTX04391 IHC-P Image

IHC-P analysis of human duodenum mucosa tissue section using GTX04391 CD8 alpha antibody [MSVA-008R] HistoMAX™.
Duodenal mucosa containing numerous intraepithelial CD8 alpha positive lymphocytes.

Anti-CD8 alpha antibody [MSVA-008R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04391

GTX04391 IHC-P Image

IHC-P analysis of human squamous cell carcinoma tissue section using GTX04391 CD8 alpha antibody [MSVA-008R] HistoMAX™.
Squamous cell carcinoma containing numerous CD8 alpha positive tumor infiltrating lymphocytes.

Anti-CD8 alpha antibody [MSVA-008R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04391

GTX04391 IHC-P Image

IHC-P analysis of human B-cell chronic lymphocytic leukemia tissue section using GTX04391 CD8 alpha antibody [MSVA-008R] HistoMAX™.
B-CLL containing interspersed non neoplastic CD8 alpha positive cells.

REFERENCE

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REVIEW

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Package List Price ($)
$ 679
$ 299