PRODUCT
Summary
This antibody was validated on 76 different Normal Tissues by IHC-P.
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:100-1:200 |
|
Note :
IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.
This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48 and BOND RX - Leica. The detailed steps by Autostainer please refer to the protocol.
|
Not tested in other applications.
Calculated MW
Positive Control
Kidney: A strong staining should be seen in distal tubuli and collecting ducts while the staining is at least moderate in proximal tubuli.
Negative Control
Colon: All cells should be CDH16 negative.
PROPERTIES
Form
Liquid
Buffer
10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format)
Preservative
0.05% sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant human full-length CDH16 protein
Purification
Protein A/G purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
cadherin 16
Cellular Localization
Cell membrane
Background
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
Database
Research Area
DATA IMAGES
![Anti-CDH16 antibody [MSVA-516R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04455](/templates/default/js/lightbox/images/loading.gif "Anti-CDH16 antibody [MSVA-516R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04455")
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GTX04455 IHC-P Image
IHC-P analysis of human thyroid tissue section using GTX04455 CDH16 antibody [MSVA-516R] HistoMAX.
CDH16 negative papillary carcinoma invading CDH16 positive normal thyroid CDH16 immunohistochemistry.
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GTX04455 IHC-P Image
IHC-P analysis of human kidney chromophobe renal cell carcinoma tissue section using GTX04455 CDH16 antibody [MSVA-516R] HistoMAX.
Chromophobe renal cell carcinoma with strong CDH16 immunostaining of tumor cells CDH16 immunohistochemistry.
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GTX04455 IHC-P Image
IHC-P analysis of human thyroid gland tissue section using GTX04455 CDH16 antibody [MSVA-516R] HistoMAX.
Strong membranous CDH16 staining of follicle cells CDH16 immunohistochemistry.
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REFERENCE
There are currently no references for CDH16 antibody [MSVA-516R] HistoMAX (GTX04455). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CDH16 antibody [MSVA-516R] HistoMAX (GTX04455). Be the first to share your experience with this product.
![Anti-CDH16 antibody [MSVA-516R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04455](/upload/website/prouct_img/small/GTX04455/GTX04455_20230728_IHC-P_5_23072722_121.webp "Anti-CDH16 antibody [MSVA-516R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04455")
![Anti-CDH16 antibody [MSVA-516R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04455](/upload/website/prouct_img/small/GTX04455/GTX04455_20230728_IHC-P_135_23072722_752.webp "Anti-CDH16 antibody [MSVA-516R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04455")
![Anti-CDH16 antibody [MSVA-516R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04455](/upload/website/prouct_img/small/GTX04455/GTX04455_20230728_IHC-P_265_23072723_346.webp "Anti-CDH16 antibody [MSVA-516R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04455")
![Anti-CDH16 antibody [MSVA-516R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04455](/upload/website/prouct_img/normal/GTX04455/GTX04455_20230728_IHC-P_5_23072722_121.webp "Anti-CDH16 antibody [MSVA-516R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04455")
![Anti-CDH16 antibody [MSVA-516R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04455](/upload/website/prouct_img/normal/GTX04455/GTX04455_20230728_IHC-P_135_23072722_752.webp "Anti-CDH16 antibody [MSVA-516R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04455")
![Anti-CDH16 antibody [MSVA-516R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04455](/upload/website/prouct_img/normal/GTX04455/GTX04455_20230728_IHC-P_265_23072723_346.webp "Anti-CDH16 antibody [MSVA-516R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04455")