GeneTex
  • Country / Location Selection

United States (US)

Caldesmon antibody [MSVA-538R] HistoMAX™

Recombinant antibody HistoMAX
Anti-Caldesmon antibody [MSVA-538R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04451
Anti-Caldesmon antibody [MSVA-538R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04451
Anti-Caldesmon antibody [MSVA-538R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04451

Cat. No. GTX04451

Host

Rabbit

Clonality

Monoclonal

Clone Name

MSVA-538R

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
500 μl ($679),
100 μl ($299)
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.

Not tested in other applications.

Calculated MW

93 kDa. ( Note )

Positive Control

Colon: A strong caldesmon staining should be seen of the muscularis mucosa and of a membrane-like layer along the basement membranes of crypts (intestinal subepithelial myofibroblasts).

Negative Control

Colon: Normal epithelial cells must not show caldesmon staining.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human full-length CALD1 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

caldesmon 1 , CDM , H-CAD , HCAD , L-CAD , LCAD , NAG22

Cellular Localization

Cytoplasm, cytoskeleton

Background

This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Caldesmon antibody [MSVA-538R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04451

GTX04451 IHC-P Image

IHC-P analysis of human uterine leiomyosarcoma tissue section using GTX04451 Caldesmon antibody [MSVA-538R] HistoMAX™.
Leiomyosarcoma showing intense Caldesmon immunostaining of tumor cells Caldesmon immunohistochemistry.

Anti-Caldesmon antibody [MSVA-538R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04451

GTX04451 IHC-P Image

IHC-P analysis of human appendix mucosa tissue section using GTX04451 Caldesmon antibody [MSVA-538R] HistoMAX™.
Intense caldesmon h positivity of intestinal subepithelial myofibroblasts ISEMFs and of the muscularis mucosae Caldesmon h immunohistochemistry.

Anti-Caldesmon antibody [MSVA-538R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04451

GTX04451 IHC-P Image

IHC-P analysis of human Breast tissue section using GTX04451 Caldesmon antibody [MSVA-538R] HistoMAX™.
Caldesmon h staining of myoepithelial cells Caldesmon h immunohistochemistry.

REFERENCE

There are currently no references for Caldesmon antibody [MSVA-538R] HistoMAX™ (GTX04451). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Caldesmon antibody [MSVA-538R] HistoMAX™ (GTX04451). Be the first to share your experience with this product.
Package List Price ($)
$ 679
$ 299