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Cystatin A antibody [MSVA-461M] HistoMAX™

HistoMAX
Anti-Cystatin A antibody [MSVA-461M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04453
Anti-Cystatin A antibody [MSVA-461M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04453
Anti-Cystatin A antibody [MSVA-461M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04453

Cat. No. GTX04453

Host

Mouse

Clonality

Monoclonal

Clone Name

MSVA-461M

Isotype

IgG2c

Application

IHC-P

Reactivity

Human
Package
500 μl ($519),
100 μl ($299)
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

Not tested in other applications.

Calculated MW

11 kDa. ( Note )

Positive Control

Skin: A strong nuclear and cytoplasmic Cystatin A immunostaining should be seen in the granular layer.

Negative Control

Colon: No epithelial cell staining should be seen. Few inflammatory cells may show Cystatin A positivity.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human CSTA protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cystatin A , AREI , PSS4 , STF1 , STFA

Cellular Localization

Cytoplasm

Background

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Cystatin A antibody [MSVA-461M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04453

GTX04453 IHC-P Image

IHC-P analysis of human rectum mucosa tissue section using GTX04453 Cystatin A antibody [MSVA-461M] HistoMAX™.
Cystatin A immunostaining is always absent in epithelial cells of the colon.

Anti-Cystatin A antibody [MSVA-461M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04453

GTX04453 IHC-P Image

IHC-P analysis of human skin tissue section using GTX04453 Cystatin A antibody [MSVA-461M] HistoMAX™.
In the skin a nuclear and cytoplasmic Cystatin A immunostaining is predominantly seen in the granular cell layer. The staining intensity decreases towards the basal cell layer.

Anti-Cystatin A antibody [MSVA-461M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04453

GTX04453 IHC-P Image

IHC-P analysis of human esophageal squamous cell carcinoma tissue section using GTX04453 Cystatin A antibody [MSVA-461M] HistoMAX™.
Squamous cell carcinoma of the esophagus showing a Cystatin A immunostaining of all tumor cells.

REFERENCE

There are currently no references for Cystatin A antibody [MSVA-461M] HistoMAX™ (GTX04453). Be the first to share your publications with this product.

REVIEW

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Package List Price ($)
$ 519
$ 299