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GATA3 antibody [MSVA-450M] HistoMAX™

HistoMAX
Anti-GATA3 antibody [MSVA-450M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04420
Anti-GATA3 antibody [MSVA-450M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04420
Anti-GATA3 antibody [MSVA-450M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04420

Cat. No. GTX04420

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MSVA-450M

Isotype

 IgG2b

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($1009),
100 μl ($299)
See all GATA3 products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50-1:100

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48 and BOND RX - Leica. The detailed steps by Autostainer please refer to the protocol.
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

Positive Control

Kidney: A moderate to strong nuclear staining reaction should be seen in a fraction of collecting duct cells and podocytes in glomeruli. ; Tonsil: The vast majority of T helper cells (Th2) in the T-zones should show a weak to moderate nuclear staining.

Negative Control

Kidney: Staining should be absent in proximal and distal tubuli as well as in blood vessels. ; Tonsil: Staining should be absent in B-cells.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human GATA-3 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

GATA binding protein 3 , HDR , HDRS

Cellular Localization

Nucleus

Background

This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009]

Database

Research Area

DATA IMAGES

Anti-GATA3 antibody [MSVA-450M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04420

GTX04420 IHC-P Image

IHC-P analysis of human muscle-invasive bladder cancer (MIBC) tissue using GTX04420 GATA3 antibody [MSVA-450M] HistoMAX™.
Muscle invasive urothelial carcinoma with moderate to strong GATA3 immunostaining of tumor cells.

Anti-GATA3 antibody [MSVA-450M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04420

GTX04420 IHC-P Image

IHC-P analysis of human renal medulla tissue using GTX04420 GATA3 antibody [MSVA-450M] HistoMAX™.
In the kidney a moderate to strong GATA3 positivity is seen in collecting ducts.

Anti-GATA3 antibody [MSVA-450M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04420

GTX04420 IHC-P Image

IHC-P analysis of human invasive breast cancer of no special type (NST) tissue using GTX04420 GATA3 antibody [MSVA-450M] HistoMAX™.
Breast cancer of no special type NST showing moderate to strong GATA3 immunostaining.

REFERENCE

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REVIEW

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Package List Price ($)
$ 1009
$ 299