APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:100-1:200 |
Not tested in other applications.
Predict Reactivity
Mouse, Rat, Zebrafish, Chicken, Xenopus tropicalis(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS, 2% BSA
Preservative
0.025% ProClin 300
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
batch dependent
Antigen Species
Human
Immunogen
Recombinant fragment of human HMGA2
Purification
Affinity purified by Protein A.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
high mobility group AT-hook 2 ,BABL ,HMGI-C ,HMGIC ,LIPO ,STQTL9
Cellular Localization
Nucleus
Background
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX639938 IHC-P Image
IHC-P analysis of human thyroid tissue using GTX639938 HMGA2 antibody [HMV314] HistoMAX™. Follicular carcinoma with strong HMGA2 staining of all tumor cells.
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GTX639938 IHC-P Image
IHC-P analysis of human uterus endocervix tissue using GTX639938 HMGA2 antibody [HMV314] HistoMAX™. Strong nuclear HMGA2 staining of epithelial cells.
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GTX639938 IHC-P Image
IHC-P analysis of human bronchus mucosa tissue using GTX639938 HMGA2 antibody [HMV314] HistoMAX™. Strong nuclear HMGA2 staining of most respiratory epithelial cells.
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REFERENCE
There are currently no references for HMGA2 antibody [HMV314] HistoMAX™ (GTX639938). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for HMGA2 antibody [HMV314] HistoMAX™ (GTX639938). Be the first to share your experience with this product.