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IL10 ELISA pair [MT60/51E6]

IL10 ELISA pair [MT60/51E6]. GTX03070

Cat No. GTX03070

Application

ELISA, Sandwich ELISA

Reactivity

Mouse
Package
1 pair ($619)
PRODUCT

Product Content

GTX02949-02
Type : Detection antibody
Host : Rat
Conjugation : Biotin
Package : 250 μg
GTX02951
Type : Capture antibody
Host : Rat
Conjugation : Unconjugated
Package : 250 μg

APPLICATION

PROPERTIES

Form

Liquid

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

interleukin 10 , CSIF , GVHDS , IL-10 , IL10A , TGIF

Cellular Localization

Secreted

Background

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]

Database

Research Area

DATA IMAGES

IL10 ELISA pair [MT60/51E6]. GTX03070

GTX03070 ELISA Image

Sandwich ELISA analysis of mouse IL-10 protein using GTX02951 IL10 antibody [MT60] as coating antibody and GTX02949-02 IL10 antibody [51E6] (Biotin) as detecting antibody.
Substrate : pNPP

REFERENCE

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REVIEW

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