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INSM1 antibody [MSVA-456R] HistoMAX™

HistoMAX
Anti-INSM1 antibody [MSVA-456R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04423
Anti-INSM1 antibody [MSVA-456R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04423
Anti-INSM1 antibody [MSVA-456R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04423

Cat. No. GTX04423

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 MSVA-456R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($679),
100 μl ($299)
See all INSM1 products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:75-1:150

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

Positive Control

Pancreas: Islet cells should show a moderate to strong INSM1 immunostaining

Negative Control

Pancreas: All acinar cells should be negative

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment (around aa81-125) corresponding to the N-terminus of human INSM1

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

INSM transcriptional repressor 1 , IA-1 , IA1

Cellular Localization

Nucleus

Background

Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-INSM1 antibody [MSVA-456R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04423

GTX04423 IHC-P Image

IHC-P analysis of human appendix tissue section using GTX04423 INSM1 antibody [MSVA-456R] HistoMAX™.
Strong INSM1 immunostaining in a low grade neuroendocrine tumor of the appendix.

Anti-INSM1 antibody [MSVA-456R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04423

GTX04423 IHC-P Image

IHC-P analysis of human adrenal gland tissue section using GTX04423 INSM1 antibody [MSVA-456R] HistoMAX™.
Strong INSM1 immunostaining of medullar but not cortical cells of the adrenal gland.

Anti-INSM1 antibody [MSVA-456R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04423

GTX04423 IHC-P Image

IHC-P analysis of human pancreas tissue section using GTX04423 INSM1 antibody [MSVA-456R] HistoMAX™.
Moderate to strong INSM1 immunostaining in most cells of Langerhans islets of the pancreas.

REFERENCE

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REVIEW

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Package List Price ($)
$ 679
$ 299