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LI-Cadherin antibody [MSVA-517M] HistoMAX™

Orthogonal HistoMAX
Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04447
Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04447
Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04447

Cat. No. GTX04447

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MSVA-517M

Isotype

 IgG2b

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($679),
100 μl ($299)
See all LI-Cadherin products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.
Not tested in other applications.

Calculated MW

92 kDa. ( Note )

Positive Control

Colon: A strong CDH17 staining should be seen in all epithelial cells.

Negative Control

Colon: Non-epithelial cells should not show any CDH17 immunostaining.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cadherin 17 , CDH16 , HPT-1 , HPT1

Cellular Localization

Cell membrane

Background

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]

Database

Research Area

DATA IMAGES

Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04447

GTX04447 IHC-P Image

IHC-P analysis of human colon colorectal adenocarcinoma tissue section using GTX04447 LI-Cadherin antibody [MSVA-517M] HistoMAX™.
Colon Colorectal adenocarcinoma with strong LI-Cadherin immunostaining of all tumor cells LI-Cadherin immunohistochemistry.

Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04447

GTX04447 IHC-P Image

IHC-P analysis of human ileum Neuroendocrine tissue section using GTX04447 LI-Cadherin antibody [MSVA-517M] HistoMAX™.
Ileum Neuroendocrine tumor with strong LI-Cadherin immunostaining of all tumor cells LI-Cadherin immunohistochemistry.

Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04447

GTX04447 IHC-P Image

IHC-P analysis of human rectum mucosa tissue section using GTX04447 LI-Cadherin antibody [MSVA-517M] HistoMAX™.
A strong membranous LI-Cadherin staining occurs in all epithelial cells of the rectum mucosa LI-Cadherin immunohistochemistry.

REFERENCE

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REVIEW

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Package List Price ($)
$ 679
$ 299