PRODUCT
Summary
This antibody was validated on 76 different Normal Tissues by IHC-P.
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:100-1:200 |
|
Note :
IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.
This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.
|
Not tested in other applications.
Calculated MW
Positive Control
Colon: A strong CDH17 staining should be seen in all epithelial cells.
Negative Control
Colon: Non-epithelial cells should not show any CDH17 immunostaining.
PROPERTIES
Form
Liquid
Buffer
10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format)
Preservative
0.05% sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17)
Purification
Protein A/G purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
cadherin 17 , CDH16 , HPT-1 , HPT1
Cellular Localization
Cell membrane
Background
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
Database
Research Area
DATA IMAGES
![Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04447](/templates/default/js/lightbox/images/loading.gif "Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04447")
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GTX04447 IHC-P Image
IHC-P analysis of human colon colorectal adenocarcinoma tissue section using GTX04447 LI-Cadherin antibody [MSVA-517M] HistoMAX.
Colon Colorectal adenocarcinoma with strong LI-Cadherin immunostaining of all tumor cells LI-Cadherin immunohistochemistry.
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GTX04447 IHC-P Image
IHC-P analysis of human ileum Neuroendocrine tissue section using GTX04447 LI-Cadherin antibody [MSVA-517M] HistoMAX.
Ileum Neuroendocrine tumor with strong LI-Cadherin immunostaining of all tumor cells LI-Cadherin immunohistochemistry.
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GTX04447 IHC-P Image
IHC-P analysis of human rectum mucosa tissue section using GTX04447 LI-Cadherin antibody [MSVA-517M] HistoMAX.
A strong membranous LI-Cadherin staining occurs in all epithelial cells of the rectum mucosa LI-Cadherin immunohistochemistry.
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REFERENCE
There are currently no references for LI-Cadherin antibody [MSVA-517M] HistoMAX (GTX04447). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for LI-Cadherin antibody [MSVA-517M] HistoMAX (GTX04447). Be the first to share your experience with this product.
![Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04447](/upload/website/prouct_img/small/GTX04447/GTX04447_20230728_IHC-P_6_23072722_542.webp "Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04447")
![Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04447](/upload/website/prouct_img/small/GTX04447/GTX04447_20230728_IHC-P_136_23072722_793.webp "Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04447")
![Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04447](/upload/website/prouct_img/small/GTX04447/GTX04447_20230728_IHC-P_266_23072722_925.webp "Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04447")
![Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04447](/upload/website/prouct_img/normal/GTX04447/GTX04447_20230728_IHC-P_6_23072722_542.webp "Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04447")
![Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04447](/upload/website/prouct_img/normal/GTX04447/GTX04447_20230728_IHC-P_136_23072722_793.webp "Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04447")
![Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04447](/upload/website/prouct_img/normal/GTX04447/GTX04447_20230728_IHC-P_266_23072722_925.webp "Anti-LI-Cadherin antibody [MSVA-517M] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04447")