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NKX2.1 antibody [MSVA-312R] HistoMAX™

Recombinant antibody HistoMAX
Anti-NKX2.1 antibody [MSVA-312R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04489
Anti-NKX2.1 antibody [MSVA-312R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04489
Anti-NKX2.1 antibody [MSVA-312R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04489

Cat. No. GTX04489

Host

Rabbit

Clonality

Monoclonal

Clone Name

MSVA-312R

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
500 μl ($679),
100 μl ($299)
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

Not tested in other applications.

Calculated MW

39 kDa. ( Note )

Positive Control

Lung: Nuclear TTF1 staining should be strong in pneumocytes and in basal cells of the terminal bronchioles while a weaker, still moderate to strong staining should be seen in columnar epithelial cells of the terminal bronchioles (low expressor control).

Negative Control

Liver: TTF1 staining must not be seen in any cells.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human TTF-1 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NK2 homeobox 1 , BCH , BHC , NK-2 , NKX2.1 , NKX2A , NMTC1 , T/EBP , TEBP , TITF1 , TTF-1 , TTF1

Cellular Localization

Nucleus

Background

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]

Database

Research Area

DATA IMAGES

Anti-NKX2.1 antibody [MSVA-312R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04489

GTX04489 IHC-P Image

IHC-P analysis of human thyroid gland tissue using GTX04489 NKX2.1 antibody [MSVA-312R] HistoMAX™.
Thyroid gland with strong NKX2.1 staining of follicular epithelial cells.

Anti-NKX2.1 antibody [MSVA-312R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04489

GTX04489 IHC-P Image

IHC-P analysis of human pneumocytes tissue using GTX04489 NKX2.1 antibody [MSVA-312R] HistoMAX™.
Intense NKX2.1 positivity of pneumocytes.

Anti-NKX2.1 antibody [MSVA-312R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04489

GTX04489 IHC-P Image

IHC-P analysis of human pulmonary adenocarcinoma tissue using GTX04489 NKX2.1 antibody [MSVA-312R] HistoMAX™.
Pulmonary adenocarcinoma with strong NKX2.1 staining of all tumor cells.

REFERENCE

There are currently no references for NKX2.1 antibody [MSVA-312R] HistoMAX™ (GTX04489). Be the first to share your publications with this product.

REVIEW

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Package List Price ($)
$ 679
$ 299