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PAX6 antibody [MSVA-706M] HistoMAX™

HistoMAX
Anti-PAX6 antibody [MSVA-706M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04487
Anti-PAX6 antibody [MSVA-706M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04487
Anti-PAX6 antibody [MSVA-706M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04487

Cat. No. GTX04487

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MSVA-706M

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($679),
100 μl ($299)
See all PAX6 products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

Positive Control

Pancreas: A strong PAX6 positivity should be seen in the cells of islets of Langerhans.

Negative Control

Tonsil: PAX6 immunostaining should be absent in all cells.

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human PAX6 fragment

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

paired box 6 , AN , AN2 , ASGD5 , D11S812E , FVH1 , MGDA , WAGR

Cellular Localization

Nucleus

Background

This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]

Database

Research Area

DATA IMAGES

Anti-PAX6 antibody [MSVA-706M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04487

GTX04487 IHC-P Image

IHC-P analysis of human pancreatic neuroendocrine tumor tissue section using GTX04487 PAX6 antibody [MSVA-706M] HistoMAX™.
Pancreatic neuroendocrine tumor with strong predominantly nuclear Pax6 positivity of all tumor cells.

Anti-PAX6 antibody [MSVA-706M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04487

GTX04487 IHC-P Image

IHC-P analysis of human pancreas tissue section using GTX04487 PAX6 antibody [MSVA-706M] HistoMAX™.
Pancreas with intense nuclear Pax6 staining of islet cells scaled.

Anti-PAX6 antibody [MSVA-706M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04487

GTX04487 IHC-P Image

IHC-P analysis of human cerebellum tissue section using GTX04487 PAX6 antibody [MSVA-706M] HistoMAX™.
Cerebellum with nuclear Pax6 staining of granule cells scaled.

REFERENCE

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REVIEW

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Package List Price ($)
$ 679
$ 299