PRODUCT
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:100-1:200 |
|
Note :
IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.
|
Not tested in other applications.
Positive Control
Skin: A strong periostin immunostaining should be seen in the skin, forming a subepithelial band of variable thickness.
Negative Control
Skin: Periostin immunostaining should be lacking in epithelial cells.
PROPERTIES
Form
Liquid
Buffer
PBS, 0.05% BSA (Please contact us for PBS only format)
Preservative
0.05% sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fragment (around aa193-326) of human POSTN protein
Purification
Protein A/G purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
periostin , OSF-2 , OSF2 , PDLPOSTN , PN
Cellular Localization
Golgi apparatus , Secreted , Secreted, extracellular space, extracellular matrix
Background
This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
Database
Research Area
DATA IMAGES
![Anti-Periostin antibody [MSVA-649M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04460](/templates/default/js/lightbox/images/loading.gif "Anti-Periostin antibody [MSVA-649M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04460")
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GTX04460 IHC-P Image
IHC-P analysis of human skin tissue using GTX04460 Periostin antibody [MSVA-649M] HistoMAX™.
Periostin is most regularly seen in a subepithelial band of variable thickness in the skin.
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GTX04460 IHC-P Image
IHC-P analysis of human invasive lobular breast cancer (ILC) tissue using GTX04460 Periostin antibody [MSVA-649M] HistoMAX™.
Abundant periostin positive stroma in an invasive lobular breast cancer.
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GTX04460 IHC-P Image
IHC-P analysis of human mucosa from rectum tissue using GTX04460 Periostin antibody [MSVA-649M] HistoMAX™.
A periostin positive subepithelial band is regularly seen in the colorectal mucosa. Additional periostin deposits occur in the lamina propria.
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REFERENCE
There are currently no references for Periostin antibody [MSVA-649M] HistoMAX™ (GTX04460). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Periostin antibody [MSVA-649M] HistoMAX™ (GTX04460). Be the first to share your experience with this product.
![Anti-Periostin antibody [MSVA-649M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04460](/upload/website/prouct_img/small/GTX04460/GTX04460_20230728_IHC-P_96_23072722_723.webp "Anti-Periostin antibody [MSVA-649M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04460")
![Anti-Periostin antibody [MSVA-649M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04460](/upload/website/prouct_img/small/GTX04460/GTX04460_20230728_IHC-P_226_23072723_514.webp "Anti-Periostin antibody [MSVA-649M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04460")
![Anti-Periostin antibody [MSVA-649M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04460](/upload/website/prouct_img/small/GTX04460/GTX04460_20230728_IHC-P_356_23072723_259.webp "Anti-Periostin antibody [MSVA-649M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04460")
![Anti-Periostin antibody [MSVA-649M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04460](/upload/website/prouct_img/normal/GTX04460/GTX04460_20230728_IHC-P_96_23072722_723.webp "Anti-Periostin antibody [MSVA-649M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04460")
![Anti-Periostin antibody [MSVA-649M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04460](/upload/website/prouct_img/normal/GTX04460/GTX04460_20230728_IHC-P_226_23072723_514.webp "Anti-Periostin antibody [MSVA-649M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04460")
![Anti-Periostin antibody [MSVA-649M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04460](/upload/website/prouct_img/normal/GTX04460/GTX04460_20230728_IHC-P_356_23072723_259.webp "Anti-Periostin antibody [MSVA-649M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04460")