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S100A12 antibody [MSVA-812M] HistoMAX™

HistoMAX
Anti-S100A12 antibody [MSVA-812M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04449
Anti-S100A12 antibody [MSVA-812M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04449
Anti-S100A12 antibody [MSVA-812M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04449

Cat. No. GTX04449

Host

Mouse

Clonality

Monoclonal

Clone Name

MSVA-812M

Isotype

IgG1

Application

IHC-P

Reactivity

Human
Package
500 μl ($679),
100 μl ($299)
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

Not tested in other applications.

Calculated MW

11 kDa. ( Note )

Positive Control

Spleen: A significant number of inflammatory cells should show a strong S100A12 immunostaining while the majority of cells remain completely negative.

Negative Control

Colon: All epithelial and muscular cells must not show any S100A12 immunostaining. Few scattered S100A12 positive inflammatory cells can occur (mostly within blood vessels)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human S100A12 fragment

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

S100 calcium binding protein A12 , CAAF1 , CAGC , CGRP , ENRAGE , MRP-6 , MRP6 , p6

Cellular Localization

Secreted , Cytoplasm , Cytoplasm, cytoskeleton , Cell membrane

Background

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity. [provided by RefSeq, Nov 2014]

Database

Research Area

DATA IMAGES

Anti-S100A12 antibody [MSVA-812M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04449

GTX04449 IHC-P Image

IHC-P analysis of human spleen tissue using GTX04449 S100A12 antibody [MSVA-812M] HistoMAX™.
S100A12 immunostaining is seen in granulocytes of mainly the red pulp.

Anti-S100A12 antibody [MSVA-812M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04449

GTX04449 IHC-P Image

IHC-P analysis of human gastric adenocarcinoma tissue using GTX04449 S100A12 antibody [MSVA-812M] HistoMAX™.
Stomach Gastric adenocarcinoma densly infiltrated by S100A12 positive granulocytes.

Anti-S100A12 antibody [MSVA-812M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04449

GTX04449 IHC-P Image

IHC-P analysis of human colorectal adenocarcinoma (COAD) tissue using GTX04449 S100A12 antibody [MSVA-812M] HistoMAX™.
Colorectal adenocarcinoma showing numerous S100A12 positive granulocytes in the stroma and within tumor glands.

REFERENCE

There are currently no references for S100A12 antibody [MSVA-812M] HistoMAX™ (GTX04449). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for S100A12 antibody [MSVA-812M] HistoMAX™ (GTX04449). Be the first to share your experience with this product.
Package List Price ($)
$ 679
$ 299