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SDHB antibody [HMV320] HistoMAX™

Recombinant antibody HistoMAX
Anti-SDHB antibody [HMV320] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639944
Anti-SDHB antibody [HMV320] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639944
Anti-SDHB antibody [HMV320] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639944

Cat. No. GTX639944

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HMV320

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($649),
100 μl ($329)
See all SDHB products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS, 2% BSA

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

batch dependent

Antigen Species

Human

Immunogen

Recombinant fragment of human SDHB.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

succinate dehydrogenase complex iron sulfur subunit B,CWS2,IP,PGL4,SDH,SDH1,SDH2,SDHIP

Background

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-SDHB antibody [HMV320] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639944

GTX639944 IHC-P Image

IHC-P analysis of human salivary gland tissue using GTX639944 SDHB antibody [HMV320] HistoMAX™.
Warthin tumor with intensive SDHB immunostaining of epithelial tumor cells.

Anti-SDHB antibody [HMV320] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639944

GTX639944 IHC-P Image

IHC-P analysis of human adrenal gland tissue using GTX639944 SDHB antibody [HMV320] HistoMAX™.
Adrenocortical carcinoma with intense SDHB staining of all tumor cells.

Anti-SDHB antibody [HMV320] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639944

GTX639944 IHC-P Image

IHC-P analysis of human liver tissue using GTX639944 SDHB antibody [HMV320] HistoMAX™.
Substantial granular cytoplasmic SDHB staining of cells, especially in hepatocytes.

REFERENCE

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REVIEW

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Package List Price ($)
$ 649
$ 329
Currently in production