PRODUCT
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:100-1:200 |
|
Note :
IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.
|
Not tested in other applications.
Calculated MW
Positive Control
Stomach: A strong cytoplasmic TFF1 staining should be seen in the gastric surface epithelium.
Negative Control
Kidney: TFF1 immunostaining should be absent in all cell types.
PROPERTIES
Form
Liquid
Buffer
PBS, 0.05% BSA (Please contact us for PBS only format)
Preservative
0.05% sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fragment (around aa1-88) of human TFF1protein
Purification
Protein A/G purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
trefoil factor 1 , BCEI , D21S21 , HP1.A , HPS2 , pNR-2 , pS2
Cellular Localization
Secreted
Background
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
![Anti-TFF1 antibody [MSVA-482M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04488](/templates/default/js/lightbox/images/loading.gif "Anti-TFF1 antibody [MSVA-482M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04488")
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GTX04488 IHC-P Image
IHC-P analysis of human mucosa from duodenum tissue using GTX04488 TFF1 antibody [MSVA-482M] HistoMAX™.
Duodenal mucosa with a moderate to strong TFF1 positivity of selected goblet cells.
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GTX04488 IHC-P Image
IHC-P analysis of human stomach tissue using GTX04488 TFF1 antibody [MSVA-482M] HistoMAX™.
Surface epithelial cells of the stomach showing an intense cytoplasmic TFF1 staining.
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GTX04488 IHC-P Image
IHC-P analysis of human pancreatic ductal adenocarcinoma (PDAC) tissue using GTX04488 TFF1 antibody [MSVA-482M] HistoMAX™.
Ductal adenocarcinoma of the pancreas with strong TFF1 staining of all tumor cells.
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REFERENCE
There are currently no references for TFF1 antibody [MSVA-482M] HistoMAX™ (GTX04488). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for TFF1 antibody [MSVA-482M] HistoMAX™ (GTX04488). Be the first to share your experience with this product.
![Anti-TFF1 antibody [MSVA-482M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04488](/upload/website/prouct_img/small/GTX04488/GTX04488_20230728_IHC-P_246_23072722_171.webp "Anti-TFF1 antibody [MSVA-482M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04488")
![Anti-TFF1 antibody [MSVA-482M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04488](/upload/website/prouct_img/small/GTX04488/GTX04488_20230728_IHC-P_376_23072723_451.webp "Anti-TFF1 antibody [MSVA-482M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04488")
![Anti-TFF1 antibody [MSVA-482M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04488](/upload/website/prouct_img/small/GTX04488/GTX04488_20230728_IHC-P_116_23072722_842.webp "Anti-TFF1 antibody [MSVA-482M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04488")
![Anti-TFF1 antibody [MSVA-482M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04488](/upload/website/prouct_img/normal/GTX04488/GTX04488_20230728_IHC-P_246_23072722_171.webp "Anti-TFF1 antibody [MSVA-482M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04488")
![Anti-TFF1 antibody [MSVA-482M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04488](/upload/website/prouct_img/normal/GTX04488/GTX04488_20230728_IHC-P_376_23072723_451.webp "Anti-TFF1 antibody [MSVA-482M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04488")
![Anti-TFF1 antibody [MSVA-482M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04488](/upload/website/prouct_img/normal/GTX04488/GTX04488_20230728_IHC-P_116_23072722_842.webp "Anti-TFF1 antibody [MSVA-482M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04488")