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TIM-3 antibody [MSVA-366R] HistoMAX

HistoMAX
Anti-TIM-3 antibody [MSVA-366R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04440
Anti-TIM-3 antibody [MSVA-366R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04440
Anti-TIM-3 antibody [MSVA-366R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04440

Cat. No. GTX04440

Host

Rabbit

Clonality

Monoclonal

Clone Name

MSVA-366R

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
500 μl ($1859),
100 μl ($459)
PRODUCT

Summary

This antibody was validated on 76 different Normal and cancerTissues by IHC-P.

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.

Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Positive Control

Tonsil: A moderate to strong TIM-3 immunostaining should be seen in a significant fraction of T-cells, while only few TIM-3 positive cells are seen in the germinal centre and the mantle zone.

Negative Control

Tonsil: Epithelial cells should be negative.

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of human TIM3 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

hepatitis A virus cellular receptor 2 , CD366 , HAVcr-2 , KIM-3 , TIM3 , TIMD-3 , TIMD3 , Tim-3

Cellular Localization

Membrane , Cell junction

Background

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]

Database

Research Area

DATA IMAGES

Anti-TIM-3 antibody [MSVA-366R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04440

GTX04440 IHC-P Image

IHC-P analysis of human uterus cervix tissue section using GTX04440 TIM-3 antibody [MSVA-366R] HistoMAX.
TIM-3 negative squamous cell carcinoma showing a large number of TIM3 positive macrophages and also lymphocytes.

Anti-TIM-3 antibody [MSVA-366R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04440

GTX04440 IHC-P Image

IHC-P analysis of human alveolar macrophages tissue section using GTX04440 TIM-3 antibody [MSVA-366R] HistoMAX.
Alveolar macrophages show strong TIM-3 immunostaining.

Anti-TIM-3 antibody [MSVA-366R] HistoMAX used in IHC (Paraffin sections) (IHC-P). GTX04440

GTX04440 IHC-P Image

IHC-P analysis of human colon descendens mucosa tissue section using GTX04440 TIM-3 antibody [MSVA-366R] HistoMAX.

REFERENCE

There are currently no references for TIM-3 antibody [MSVA-366R] HistoMAX (GTX04440). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for TIM-3 antibody [MSVA-366R] HistoMAX (GTX04440). Be the first to share your experience with this product.
Package List Price ($)
$ 1859
$ 459