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TMEM16A antibody [MSVA-201M] HistoMAX™

HistoMAX
Anti-TMEM16A antibody [MSVA-201M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04369
Anti-TMEM16A antibody [MSVA-201M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04369
Anti-TMEM16A antibody [MSVA-201M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04369

Cat. No. GTX04369

Host

Mouse

Clonality

Monoclonal

Clone Name

MSVA-201M

Isotype

IgG2b

Application

IHC-P

Reactivity

Human
Package
500 μl ($769),
100 μl ($299)
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 9.0 Tris-EDTA-based Target Retrieval Solution buffer. Based on the testing result, the pH 9.0 showed a strongest staining pattern. The pH 7.8 is acceptable but lower pH results in a significant reduction of sensitivity.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.

Not tested in other applications.

Calculated MW

114 kDa. ( Note )

Positive Control

Appendix: An at least moderate, predominantly membranous staining should be seen in Cajal cells in the muscular wall and a weak membranous staining should be seen in columnar epithelial cells in the basal part of the crypts of the appendix.

Negative Control

Appendix: Staining should be absent in the majority of cells in the muscular wall and in epithelial cells located at the surface.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human DOG-1 protein fragment (aa 2-101)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

anoctamin 1 , DOG1 , ORAOV2 , TAOS2 , TMEM16A

Cellular Localization

Cell membrane , Cytoplasm

Background

Enables calcium activated cation channel activity; intracellular calcium activated chloride channel activity; and iodide transmembrane transporter activity. Involved in cation transport; inorganic anion transport; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in apical plasma membrane and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Database

Research Area

DATA IMAGES

Anti-TMEM16A antibody [MSVA-201M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04369

GTX04369 IHC-P Image

IHC-P analysis of human gastrointestinal stromal tumor (GIST) tissue using GTX04369 TMEM16A antibody [MSVA-201M] HistoMAX™.
DOG1 Tumor periphery of a GIST showing intensive TMEM16A staining in all tumor cells.

Anti-TMEM16A antibody [MSVA-201M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04369

GTX04369 IHC-P Image

IHC-P analysis of human seminal vesicle tissue using GTX04369 TMEM16A antibody [MSVA-201M] HistoMAX™.
Strong TMEM16A staining of apical membranes of glandular cells.

Anti-TMEM16A antibody [MSVA-201M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04369

GTX04369 IHC-P Image

IHC-P analysis of human parotid gland tissue using GTX04369 TMEM16A antibody [MSVA-201M] HistoMAX™.
Strong TMEM16A staining of the apical membranes of secreting cells.

REFERENCE

There are currently no references for TMEM16A antibody [MSVA-201M] HistoMAX™ (GTX04369). Be the first to share your publications with this product.

REVIEW

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Package List Price ($)
$ 769
$ 299