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TRPS1 antibody [MSVA-512R] HistoMAX™

HistoMAX
Anti-TRPS1 antibody [MSVA-512R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04485
Anti-TRPS1 antibody [MSVA-512R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04485
Anti-TRPS1 antibody [MSVA-512R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04485

Cat. No. GTX04485

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 MSVA-512R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($679),
100 μl ($299)
See all TRPS1 products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.
Not tested in other applications.

Calculated MW

142 kDa. ( Note )

Positive Control

Breast: A strong TRPS1 staining should be seen in luminal breast epithelial cells. (For low-level TRPS1 detection: Testis: A weak nuclear TRPS1 staining should be seen in spermatogonia.)

Negative Control

Colon: Nuclear TRPS1 staining should be absent in epithelial cells.

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment (around aa900-1100) of human TRPS1 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transcriptional repressor GATA binding 1 , GC79 , LGCR

Cellular Localization

Nucleus

Background

This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TRPS1 antibody [MSVA-512R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04485

GTX04485 IHC-P Image

IHC-P analysis of human invasive breast cancer tissue section using GTX04485 TRPS1 antibody [MSVA-512R] HistoMAX™.
Invasive breast cancer of no special type NST with intense nuclear TRPS1 positivity.
Dilution : 1: 600

Anti-TRPS1 antibody [MSVA-512R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04485

GTX04485 IHC-P Image

IHC-P analysis of human Breast tissue section using GTX04485 TRPS1 antibody [MSVA-512R] HistoMAX™.
Intense nuclear TRPS1 staining of luminal but not basal breast epithelial cells.
Dilution : 1:20

Anti-TRPS1 antibody [MSVA-512R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04485

GTX04485 IHC-P Image

IHC-P analysis of human appendical epithelial cells tissue section using GTX04485 TRPS1 antibody [MSVA-512R] HistoMAX™.
Dilution : 1:20

REFERENCE

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REVIEW

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Package List Price ($)
$ 679
$ 299