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Summary The full-length Insulin Receptor includes the 27 aa signal peptide that is cleaved during maturation. The Tyr1322 of mature Insulin Receptor (P06213-2) is equivalent to Tyr1349 of uncleaved Insulin Receptor or Tyr1361 of uncleaved Insulin Receptor (P06213-1)..

Summary The epitope recognized by this antibody has been studied extensively and would appear to include the carboxy-terminus of the alpha-2 helix and a turn on one of the underlying beta strands.