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Summary This antibody reacts with CD53, a 32-40 kDa tetraspanin family glycoprotein exclusivelly expressed on leukocytes. And this antibody also reacts with deglycosylated molecule (molecular weight of the antigen is reduced by 15 kDa using endoglycosidase F).

Summary This antibody recognizes a protein of 18kDa, identified at Melan A (Melanoma Antigen Recognized by T- cells 1) or Melan-A. The MART-1 recognizes a subcellular fraction found in melanosomes. The antibody labels melanomas and tumors showing melanocytic differentiation. It does not mark neoplasms of epithelial origin, lymphomas or mesenchymal tumors. Melan-A is a useful addition to melanoma panels as it is apparently specific for melanocytic lesions. Both HMB-45 and MART-1 are coexpressed in the majority of melanomas, as well as uniquely expressed in certain cases. Studies have shown that MART-1 is more sensitive than HMB-45 when labeling metastatic melanomas.

Summary Please note that this MAb is of Armenian Hamster origin and use the appropriate secondary Ab (from Jackson ImmunoResearch) for all applications.

Summary Pre-adsorbed with Bovine, Horse and Human serum proteins. May react with immunoglobulins from other species.

Summary This antibody has been pre-adsorbed against Mouse, Chicken, Cow, Goat, Guinea pig, Hamster, Horse, Rabbit, Rat and Sheep serum proteins to ensure minimal cross-reactivity. Cross-reactivity with other species, however, is possible.

Summary This antibody has been pre-adsorbed against Bovine, Chicken, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, and Sheep serum proteins to ensure minimal cross-reactivity. Cross-reactivity with other species, however, is possible.