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Summary Recognizes classical class I antigen, detecting a public specificity shared by both loci K and D.

Summary The R6-5-D6 antibody has been reported to inhibit the interaction of CD54 with leukocytes, thereby decreasing leukocyte adhesion to the vascular endothelium and inflammatory tissue injury.

Summary Recognises a polymorphic determinant (c haplotype) of rat Class I MHC Antigen (RT-1A).

Summary This antibody recognizes the canine homologue of CD34, a glycosylated type 1 transmembrane protein of approximately 110 kDa (McSweeney et al. 1998) expressed on the cell suface of endothelial cells and haematopoietic stem cells.
It is a key marker of canine hematopoietic progenitor cells and is reported for use in CD34+ enrichment assays, (Goerner et al. 2001) and (Horn et al. 2004).