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Summary This antibody reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes; also expressed by most tissue macrophages. And this antibody also reacts with soluble forms of CD14 found in serum and in the urine of some nephrotic patients.