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Summary This antibody recognizes common epitope on beta-chain of human HLA-DR and HLA-DP.

Summary This antibody recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.

Summary This antibody recognizes an epitope different from the ones recognized by BE5 and 4H10 antibodies to IgE. The epitope is located within the amino acids 103-115 (WSDYNFDYSSSEE).

Summary This antibody recognizes a conformationally-dependent epitope of CD8. The antibody does not react with formaldehyde-fixed cells; negative in Western blotting application.

Summary The YTS 177 antibody has been shown to compete with clones GK1.5 and YTS 191 for CD4 binding. The YTS 177 antibody has been reported to be non-depleting but binding does induce rapid internalization of CD4 on both CD4+ Foxp3- T cells and Foxp3+ regulatory T cells. Further, the YTS 177 clone has been shown to suppress or even prevent allograft rejection, allergic reactions and autoimmune responses.

Summary This antibody recognizes all polymorphic forms of chicken CD8 alpha.