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Summary By immunoblotting and ELISA, the antibody shows 30% cross-reactivity with recombinant mouse GM-CSF and 10% cross-reactivity with recombinant human GM-CSF.

Summary This monoclonal antibody reacts with natural and recombinant human MCP 3. It does not show any cross reaction with other human cytokines or growth factors tested such as IL 1 beta, IL 8, MCAF, SAA and EGF.

Summary Reacts with endogenous and recombinant human SAA. Does not cross-react with other human cytokines or growth factors tested such as IL1?, IL8, MCAF, TGF? and EGF.

Summary Does not cross-react with MBP or BSA.

Summary Recognizes mouse BAFF Receptor.

Summary The molecular weight of the recognized antigen is 55kDa. The IL-2 receptor consists of at least three distinct membrane components: the alpha chain (IL-2R alpha, Tac, CD25), the beta chain (IL-2R beta, p75, CD122), and the gamma chain (IL-2R gamma). CD25 is undetectable on resting T cells but is induced upon T-cell activation. B1.49.9 recognizes activated T and B cells. CD25 is absent on thymocytes, resting T and B cells, and NK cells. B1.49.9 does not inhibit the in vitro IL2 dependent proliferation