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Summary Clone 2F8 is unsuitable for use with the C57BL/6 mouse strain (Daugherty et al. 2000).

Summary Neutralizes the biological activity of recombinant human MCP-2. Shows <20% cross-reactivity with recombinant human MCP-1 and recombinant mouse MIP-1α.

Summary Detects a monomorphic determinant on HLA-DR, a human Class II histocompatability antigen. Reacts with B lymphocytes, monocytes, macrophages, activated T cells, thymic epithelium, B cell dependent areas of spleen and lymph nodes, and B cell lymphomas. It inhibits T cell function at the clonal level.