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Summary Using indirect immunofluorescence assay and ELISA, this monoclonal antibody showed positive reaction with lung adenocarcinoma, squamous cancer and small cell carcinoma. It is also positive to some human melanoma and other tumours. This antibody does not cross reacts with human adult normal tissues and fetal tissues.

Summary The dominant epitope of this antibody involves both amino acids as well as sugar moieties. Its epitope is destroyed by desialylation i.e. treatment with Neuraminidase.