Cancer Tissue Gallery- GTX646253

Bcl-XL antibody [HMV4724] HistoMAX™

 

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Breast – BCL-XL negative invasive lobular breast cancer.

Breast – Invasive breast cancer of no special type (NST) with strong, cytoplasmic BCL-XL staining of tumor cells.

Breast – Invasive lobular breast cancer with distinct cytoplasmic BCL-XL positivity of tumor cells.

Colon – Colorectal adenocarcinoma with strong cytoplasmic BCL-XL staining of tumor cells.

       

Kidne – Oncocytoma with strong, cytoplasmic BCL-XL staining of all tumor cells.

Kidney – Clear cell renal cell carcinoma with faint-weak, cytoplasmic BCL-XL positivity of a fraction of tumor cells.

Kidney – Papillary renal cell carcinoma with moderate, cytoplasmic BCL-XL positivity of tumor cells.

Lung – Malignant mesothelioma with heterogeneous, moderate to strong, cytoplasmic BCL-XL positivity of tumor cells.

       

Lung – Adenocarcinoma with strong cytoplasmic BCL-XL immunostaining of tumor cells.

Lung – Adenocarcinoma with strong cytoplasmic BCL-XL staining of tumor cells.

Lung – Squamous cell carcinoma with heterogeneous, weak to moderate, cytoplasmic BCL-XL positivity of tumor cells.

Oral cavity – BCL-XL negative squamous cell carcinoma.

       

Oral cavity – Squamous cell carcinoma with weak to moderate, cytoplasmic BCL-XL staining of tumor cells, especially at the periphery of tumor cell nests.

Ovary – Clear cell carcinoma with faint cytoplasmic BCL-XL staining of only few tumor cells.

Ovary – Endometroid carcinoma with strong, cytoplasmic BCL-XL staining of tumor cells.

Ovary – Serous high-grade carcinoma with intense, cytoplasmic BCL-XL positivity of all tumor cells.

       

Pharynx – Squamous cell carcinoma with faint BCL-XL immunostaining of a subset of tumor cells.

Prostate – Adenocarcinoma (Gleason 4+4=8) with weak cytoplasmic BCL-XL staining of a subset of tumor cells.

Prostate – Adenocarcinoma (Gleason 4+4=8) with weak to moderate cytoplasmic BCL-XL immunostaining of tumor cells.

Prostate – Adenocarcinoma (Gleason 5+5=10) with only faint cytoplasmic BCL-XL immunostaining of most tumor cells.

       

Testis – BCL-XL negative seminoma. Distinct BCL-XL positivity of a subset of tumor associated inflammatory cells.

Thyroid – Papillary cancer with intense cytoplasmic BCL-XL staining of all tumor cells.

Urinary bladder – Muscle-invasive urothelial carcinoma with strong, cytoplasmic BCL-XL staining of all tumor cells.

Urinary bladder – Non-invasive urothelial carcinoma (low grade, pTaG2) with moderate to strong, cytoplasmic BCL-XL staining of tumor cells.

       

Urinary bladder – Non-invasive urothelial carcinoma (low grade, pTaG2) with moderate, cytoplasmic BCL-XL staining of most tumor cells.

 

 

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