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Kallikrein 7 antibody [MSVA-707M] HistoMAX™

Comparison Orthogonal HistoMAX
Anti-Kallikrein 7 antibody [MSVA-707M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04475
Anti-Kallikrein 7 antibody [MSVA-707M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04475
Anti-Kallikrein 7 antibody [MSVA-707M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04475

Cat. No. GTX04475

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MSVA-707M

Isotype

 IgG2b

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($679),
100 μl ($299)
See all Kallikrein 7 products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

Positive Control

Skin: A strong KLK7 staining should be seen in the stratum granulosum and possibly also in the keratinizing cell layers.

Negative Control

Colon: KLK7 immunostaining should be absent in all cells of the colon mucosa

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human KLK7 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

kallikrein related peptidase 7 , PRSS6 , SCCE , hK7

Cellular Localization

Secreted

Background

This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]

Database

Research Area

DATA IMAGES

Anti-Kallikrein 7 antibody [MSVA-707M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04475

GTX04475 IHC-P Image

IHC-P analysis of human squamous cell carcinoma tissue section using GTX04475 Kallikrein 7 antibody [MSVA-707M] HistoMAX™.
Squamous cell carcinoma showing strong Kallikrein 7 staining in areas of keratinization.

Anti-Kallikrein 7 antibody [MSVA-707M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04475

GTX04475 IHC-P Image

IHC-P analysis of human colon mucosa tissue section using GTX04475 Kallikrein 7 antibody [MSVA-707M] HistoMAX™.
Kallikrein 7 staining is absent in all cells of the colon mucosa.

Anti-Kallikrein 7 antibody [MSVA-707M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04475

GTX04475 IHC-P Image

IHC-P analysis of human skin tissue section using GTX04475 Kallikrein 7 antibody [MSVA-707M] HistoMAX™.
A strong Kallikrein 7 staining in the stratum granulosum and the keratinizing superficial layer of the skin.

REFERENCE

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REVIEW

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Package List Price ($)
$ 679
$ 299