PRODUCT
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:100-1:200 |
|
Note :
IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.
|
Not tested in other applications.
Calculated MW
Positive Control
Kidney: At least weak to moderate, distinct nuclear staining should be seen in the majority of epithelial cells of the proximal and distal renal tubules, collection ducts, and the parietal epithelial cells of the Bowman’s capsule.
Negative Control
Kidney: At least weak to moderate, distinct nuclear staining should be seen in the majority of epithelial cells of the proximal and distal renal tubules, collection ducts, and the parietal epithelial cells of the Bowman’s capsule.
PROPERTIES
Form
Liquid
Buffer
PBS, 0.05% BSA (Please contact us for PBS only format)
Preservative
0.05% sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fragment of human PAX8 protein
Purification
Protein A/G purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
paired box 8
Cellular Localization
Nucleus
Background
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]
Database
Research Area
DATA IMAGES
![Anti-PAX8 antibody [MSVA-708R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04430](/templates/default/js/lightbox/images/loading.gif "Anti-PAX8 antibody [MSVA-708R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04430")
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GTX04430 IHC-P Image
IHC-P analysis of human lymph node tissue using GTX04430 PAX8 antibody [MSVA-708R] HistoMAX™.
PAX8 staining is completely absent in lymphocytes lymph node.
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GTX04430 IHC-P Image
IHC-P analysis of human high-grade serous ovarian cancer (HGSOC) tissue using GTX04430 PAX8 antibody [MSVA-708R] HistoMAX™.
Serous high grade ovarian carcinoma with strong PAX8 staining of tumor cells.
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GTX04430 IHC-P Image
IHC-P analysis of human fallopian tube tissue using GTX04430 PAX8 antibody [MSVA-708R] HistoMAX™.
Strong nuclear PAX8 staining of a subset of epithelial cells in the fallopian tube.
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REFERENCE
There are currently no references for PAX8 antibody [MSVA-708R] HistoMAX™ (GTX04430). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PAX8 antibody [MSVA-708R] HistoMAX™ (GTX04430). Be the first to share your experience with this product.
![Anti-PAX8 antibody [MSVA-708R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04430](/upload/website/prouct_img/small/GTX04430/GTX04430_20230728_IHC-P_224_23072722_456.webp "Anti-PAX8 antibody [MSVA-708R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04430")
![Anti-PAX8 antibody [MSVA-708R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04430](/upload/website/prouct_img/small/GTX04430/GTX04430_20230728_IHC-P_354_23072723_760.webp "Anti-PAX8 antibody [MSVA-708R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04430")
![Anti-PAX8 antibody [MSVA-708R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04430](/upload/website/prouct_img/small/GTX04430/GTX04430_20230728_IHC-P_94_23072722_863.webp "Anti-PAX8 antibody [MSVA-708R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04430")
![Anti-PAX8 antibody [MSVA-708R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04430](/upload/website/prouct_img/normal/GTX04430/GTX04430_20230728_IHC-P_224_23072722_456.webp "Anti-PAX8 antibody [MSVA-708R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04430")
![Anti-PAX8 antibody [MSVA-708R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04430](/upload/website/prouct_img/normal/GTX04430/GTX04430_20230728_IHC-P_354_23072723_760.webp "Anti-PAX8 antibody [MSVA-708R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04430")
![Anti-PAX8 antibody [MSVA-708R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04430](/upload/website/prouct_img/normal/GTX04430/GTX04430_20230728_IHC-P_94_23072722_863.webp "Anti-PAX8 antibody [MSVA-708R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04430")