Search Results

Summary It reacts with: 4 Serovars of Leptospira interrogans + 2 Serovars of L. kirschneri and does not react with Lepospira biflexa (as expected) and mammalian cells.

Summary The 3DT-52.5 TcR idiotype in Mouse

Summary This antibody reacts with CD53, a 32-40 kDa tetraspanin family glycoprotein exclusivelly expressed on leukocytes. And this antibody also reacts with deglycosylated molecule (molecular weight of the antigen is reduced by 15 kDa using endoglycosidase F).

Summary This antibody recognizes a protein of 18kDa, identified at Melan A (Melanoma Antigen Recognized by T- cells 1) or Melan-A. The MART-1 recognizes a subcellular fraction found in melanosomes. The antibody labels melanomas and tumors showing melanocytic differentiation. It does not mark neoplasms of epithelial origin, lymphomas or mesenchymal tumors. Melan-A is a useful addition to melanoma panels as it is apparently specific for melanocytic lesions. Both HMB-45 and MART-1 are coexpressed in the majority of melanomas, as well as uniquely expressed in certain cases. Studies have shown that MART-1 is more sensitive than HMB-45 when labeling metastatic melanomas.