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Summary This antibody reacts with the high molecular weight form of the leucocyte common antigen (LCA) expressed by B lymphocytes and a subset of T lymphocytes.

Summary This antibody recognizes the HLA-B7 antigen and does not cross-react with HLA-B27 or other related antigens.It can be used to distinguish true HLA B27 positives from false HLA B27 positives (i.e. HLA B7 positive) in the investigation of diseases such as ankylosing spondylitis and anterior uveitis.

Summary This antibody recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.

Summary Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum, Human IgG and Human Serum.

Summary This antibody recognises human lambda light chains and has been cross absorbed with pooled human myeloma proteins with kappa light chains.

Summary The molecular weight of the recognized antigen is 55kDa. The IL-2 receptor consists of at least three distinct membrane components: the alpha chain (IL-2R alpha, Tac, CD25), the beta chain (IL-2R beta, p75, CD122), and the gamma chain (IL-2R gamma). CD25 is undetectable on resting T cells but is induced upon T-cell activation. B1.49.9 recognizes activated T and B cells. CD25 is absent on thymocytes, resting T and B cells, and NK cells. B1.49.9 does not inhibit the in vitro IL2 dependent proliferation