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Summary This antibody recognizes both the alpha 1 and the alpha 2 isoforms of AMP-activated protein kinase (AMPK).

Summary The monoclonal antibody M2139 reacts with the J1 epitope (triple helical position 551-564) of collagen type II. Collagen is a structural protein in bone, cartillage and connective tissue. The monocolonal antibody M2139 has been shown to induce CAIA in naïve mice after injection of lipopolysacharide (LPS). However, in combination with the monoclonal antibody CIIC1, binding to the C1 epitope of CII, the pair of monoclonal antibodies induce arthritis in different strains of mice without any other stimulants. The presence of secondary stimulus, LPS, increases the disease incidence and severity.

Summary This antibody detects an ~127 kDa protein and an ~133 kDa protein representing PMCA2a and PMCA2b ATPase, respectively, from rat brain microsomal fractions.