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Summary This antibody reacts with CD53, a 32-40 kDa tetraspanin family glycoprotein exclusivelly expressed on leukocytes. And this antibody also reacts with deglycosylated molecule (molecular weight of the antigen is reduced by 15 kDa using endoglycosidase F).

Summary The molecular weight of the recognized platelet form of CD63 is 40 to 55 kDa. CLBGran/12 reacts withmost peripheral blood cells including activated platelets, lymphoid, myeloid and endothelial cells, except forred blood cells and resting T cells. The CD63 antigen is present in many tissues and cell line PHA blasts,K562, U937, KG1a, RAJI. Both surface and cytoplasmotic reactions are reported. CLB Gran/12 has beenassigned to the CD63 cluster of differentiation at the IVth International Workshop on Human LeucocyteDifferentiation Antigens.