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Summary The full-length Insulin Receptor includes the 27 aa signal peptide that is cleaved during maturation. The Tyr1316 of mature Insulin Receptor (P06213-2) is equivalent to Tyr1343 of uncleaved Insulin Receptor (P06213-2) or Tyr1355 of uncleaved Insulin Receptor (P06213-1).

Summary This antibody reacts with Kupffer cells and sinus lining cells on the liver. Skin  Langerhans  cells  are  always  negative   (Hogg et al. 1984).