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Summary This antibody shows strong reaction in RIA with hCG and hCG beta. Some reactivity was found on hLH (12%) and hLH beta (34%). No reaction with hFSH, hTSH, hCG alpha and hLH alpha.

Summary This antibody recognizes a protein of 18kDa, identified at Melan A (Melanoma Antigen Recognized by T- cells 1) or Melan-A. The MART-1 recognizes a subcellular fraction found in melanosomes. The antibody labels melanomas and tumors showing melanocytic differentiation. It does not mark neoplasms of epithelial origin, lymphomas or mesenchymal tumors. Melan-A is a useful addition to melanoma panels as it is apparently specific for melanocytic lesions. Both HMB-45 and MART-1 are coexpressed in the majority of melanomas, as well as uniquely expressed in certain cases. Studies have shown that MART-1 is more sensitive than HMB-45 when labeling metastatic melanomas.

Summary This antibody recognizes the beta 1 epitope on human chorionic gonadotrophin (hCG). Clone INN-hCG-2 is reactive with hCG, hCG beta, hCG betacf (fragment), hCGn (nicked), hCG betan, and CTP-hCG. No cross reaction is observed with hLH, hLHbeta, hFSH, hTSH,or the glycoprotein hormone alpha chains.