Normal Tissue Gallery- GTX04370

Adrenal gland - Chromogranin A staining is absent in the cortex.

Adrenal gland - Intense chromogranin A staining in all cells of the medulla.

Aorta, media

Appendix, mucosa

Appendix, muscular wall - Weak chromogranin A immunostaining is seen in axons and ganglion cells of the peripheral nerves.

Bone marrow

Breast

Cerebellum (molecular layer, Purkinje cell layer, granule cell layer, white matter)

Cerebellum (granule cell layer, white matter)

Cerebrum, grey matter

Cerebrum, white matter

Colon descendens, mucosa

Colon descendens, muscular wall

Duodenum, Brunner gland

Duodenum, mucosa - Strong chromogranin A immunostaining of neuroendocrine cells. Due to the high level of chromogranin A protein in these cells, adjacent non-neuroendocrine cells show "contamination artifacts".

Ectocervix

Endocervix

Endocervix - Few neuroendocrine cells are chromogranin A positive.

Endometrium, proliferation

Endometrium, secretion

Epididymis

Esophagus, squamous epithelium

Fallopian tube, mucosa

Fat

Gallbladder, epithelium

Heart

Ileum, mucosa

Kidney, cortex

Kidney, medulla

Liver

Lung

Lymph node

Ovary, stroma

Pancreas - Strong chromogranin A positivity in islets of Langerhans.

Parathyroid gland - Strong chromogranin A staining of epithelial cells.

Parotid gland

Pituitary gland, anterior lobe - Strong chromogranin A staining of epithelial cells.

Pituitary gland, posterior lobe

Pregnant uterus (decidua)

Placenta, early

Placenta, mature

Placenta (amnion and chorion)

Prostate

Seminal vesicle

Sinus paranasales

Skin - Few neuroendokrine (Merkel-) cells show chromogranin A immunostaining.

Spleen

Stomach, antrum

Stomach, corpus

Stomach, corpus - Expression of chromogranin A is so strong in neuroendocrine cells of the stomach, that diffusion of the staining product towards adjacent cells can occur.

Testis

Thymus

Thyroid gland

Tongue, muscle

Tonsil, surface epithelium

Tonsil

Urinary bladder, muscular wall

Urinary bladder, urothelium

Uterus, myometrium