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Summary This antibody recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.

Summary Recognises HIV-2 Nef and does not cross react with HIV-1 Nef

Summary Reacts with the heavy and light chains of rabbit IgG and the light chains of rabbit IgM. Pre-adsorbed with Mouse, rat, and human immunoglobulins and pooled sera. May react with immunoglobulins from other species

Summary The antibody reacts with human CCR-6 transfectant cells and not the parent cell line. The antibody shows no cross-reactivity with CCR-1, CCR-2, CCR-3, CCR-4, CCR-5, CCR-7, CXCR-1, CXCR-2, CXCR-3, CXCR-4 or STRL33.

Summary In immunoblotting, the antibody exhibits ~5% cross-reactivity with recombinant rat EphB1 and EphA5, recombinant mouse EphA8, EphB6, EphA3, EphA4, EphA7, EphA2, EphB3, and recombinant human EphA1.