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Summary Specifically reacts with the 515 kDa alpha-chain of human LRP/alpha2 MR expressed in certain cell types. A strongimmunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurons and astrocytes in theCNS, fibroblasts, smooth muscle cells and monocyte-derived foam cells in atherosclerotic lesions of arterial walls.Will block a2M binding.

Summary This antibody reacts with a monomorphic epitope of the 45 kD polypeptide, constiituting the HLAA,-B and-C or class I antigen of the human major histocompatibility complex.