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Cancer Metabolism

Cancer Metabolism

Cancer Metabolism

Nearly a century ago, Otto Warburg found that cancer cells can shift their energy production to aerobic glycolysis instead of the more efficient oxidative phosphorylation. An emerging hallmark of many cancers is their metabolic plasticity, as rewiring of cancer cells' metabolic fluxes is essential for their proliferative and invasive agenda. With increasing understanding of these alterations, researchers are identifying features of tumor metabolism that can be used for novel diagnostic, prognostic, and therapeutic opportunities.
Highlighted Products
   
IDH1 antibody

IDH1 antibody  (GTX629818)
IDH2 antibody

IDH2 antibody  (GTX628487)
 
LDHA antibody

LDHA antibody (GTX101416)
Hexokinase 1 antibody

Hexokinase 1 antibody (GTX105248)
PKM antibody

PKM antibody (GTX107977)
  
Pyruvate Dehydrogenase E1 alpha antibody

Pyruvate Dehydrogenase E1 alpha antibody (GTX104015)
 

 

Newsletter
Article Alert: IFNγ-stimulated KAT8-IRF1 Condensates Activate PD-L1 Expression and Promote Immune Evasion

IFNγ-stimulated KAT8-IRF1 Condensates Activate PD-L1 Expression and Promote Immune Evasion

Newsletter
PARPs as Therapeutic Targets in Clinical Oncology

PARPs as Therapeutic Targets in Clinical Oncology

Newsletter
HCK Inhibition: Boosting Immunotherapy’s Efficacy and Utility?

HCK Inhibition: Boosting Immunotherapy’s Efficacy and Utility?

Newsletter
Article Alert: C3aR and TNF-αR Antagonists as Potential Therapies for Medulloblastoma

Article Alert: C3aR and TNF-αR Antagonists as Potential Therapies for Medulloblastoma

Newsletter
ADAM17: A Major “Sheddase” in Human Disease

ADAM17: A Major “Sheddase” in Human Disease

ADAM17: A Major “Sheddase” in Human Disease
Newsletter
Carbonic Anhydrase IX (CA IX): Acid-Base Regulator and Driver of Tumorigenesis

Carbonic Anhydrase IX (CA IX): Acid-Base Regulator and Driver of Tumorigenesis

Carbonic anhydrase IX (CA IX) is a transmembrane, hypoxia-induced zinc metalloenzyme that converts carbon dioxide to bicarbonate and protons...
Newsletter

A Rising StAR in Cancer Research

Steroidogenic acute regulatory protein 1 (StAR/StARD1) mediates the rate-limiting step in steroidogenesis...
Newsletter

NEK7: An Essential Regulator of NLRP3 Inflammasome Activation

NEK7: An Essential Regulator of NLRP3 Inflammasome Activation
Newsletter
Nuclear PD-L1 Mediates Pyroptosis in Cancer Cells

Nuclear PD-L1 Mediates Pyroptosis in Cancer Cells

Nuclear PD-L1 Mediates Pyroptosis in Cancer Cells
Newsletter

Lateral Flow Assay for Influenza & SARS-CoV-2 Viruses Detection

Influenza A & B Virus Antibodies (IVD grade)
Literature
Brochure - Cited Antibodies

Brochure - Cited Antibodies

Download the latest version of GeneTex's Cited Antibodies brochure.
Newsletter
New Therapeutic Paradigm for Cancers with Activated NRF2

New Therapeutic Paradigm for Cancers with Activated NRF2

New Therapeutic Paradigm for Cancers with Activated NRF2
Literature

Flyer-Cancer

Download the latest version of GeneTex's Cancer flyer.
Newsletter
GeneTex Launches Novel Recombinant RAS (G12D Mutant) Antibody [HL10]

GeneTex Launches Novel Recombinant RAS (G12D Mutant) Antibody [HL10]

GeneTex's RAS (G12D mutant) recombinant antibody is suitable for IHC staining and WB.
Literature
Download the latest version of GeneTex's Zika Virus Research flyer.

Flyer-Zika Virus Research

Download the latest version of GeneTex's Zika Virus Research flyer.
Literature
Cited Antibodies

Flyer - Cited Antibodies

Download the latest version of GeneTex's cited antibodies flyer.
Newsletter

A Cancer Immunotherapy Holy Grail?

A Cancer Immunotherapy Holy Grail?
Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
Literature
Cancer Signaling

Poster - Cancer Signaling

Download the latest version of GeneTex's cancer signaling poster
Literature
Antibodies for Cancer Research

Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research
Literature
Metabolic Pathways

Flyer - Metabolic Pathways

Download the latest version of GeneTex's metabolic pathways flyer.
Literature

Flyer - RNA-binding Proteins

Download the latest version of GeneTex's RNA-binding proteins flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature
Cancer Immune Checkpoint

Flyer - Cancer Immune Checkpoints

Download the latest version of GeneTex's cancer immune checkpoint flyer
Literature
Brochure - Cited Antibodies

Brochure - Cited Antibodies

Download the latest version of GeneTex's Cited Antibodies brochure.
Literature

Flyer-Cancer

Download the latest version of GeneTex's Cancer flyer.
Literature
Download the latest version of GeneTex's Zika Virus Research flyer.

Flyer-Zika Virus Research

Download the latest version of GeneTex's Zika Virus Research flyer.
Literature
Cited Antibodies

Flyer - Cited Antibodies

Download the latest version of GeneTex's cited antibodies flyer.
Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
Literature
Cancer Signaling

Poster - Cancer Signaling

Download the latest version of GeneTex's cancer signaling poster
Literature
Antibodies for Cancer Research

Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research
Literature
Metabolic Pathways

Flyer - Metabolic Pathways

Download the latest version of GeneTex's metabolic pathways flyer.
Literature

Flyer - RNA-binding Proteins

Download the latest version of GeneTex's RNA-binding proteins flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature
Cancer Immune Checkpoint

Flyer - Cancer Immune Checkpoints

Download the latest version of GeneTex's cancer immune checkpoint flyer
Newsletter
Article Alert: IFNγ-stimulated KAT8-IRF1 Condensates Activate PD-L1 Expression and Promote Immune Evasion

IFNγ-stimulated KAT8-IRF1 Condensates Activate PD-L1 Expression and Promote Immune Evasion

Newsletter
PARPs as Therapeutic Targets in Clinical Oncology

PARPs as Therapeutic Targets in Clinical Oncology

Newsletter
HCK Inhibition: Boosting Immunotherapy’s Efficacy and Utility?

HCK Inhibition: Boosting Immunotherapy’s Efficacy and Utility?

Newsletter
Article Alert: C3aR and TNF-αR Antagonists as Potential Therapies for Medulloblastoma

Article Alert: C3aR and TNF-αR Antagonists as Potential Therapies for Medulloblastoma

Newsletter
ADAM17: A Major “Sheddase” in Human Disease

ADAM17: A Major “Sheddase” in Human Disease

ADAM17: A Major “Sheddase” in Human Disease
Newsletter
Carbonic Anhydrase IX (CA IX): Acid-Base Regulator and Driver of Tumorigenesis

Carbonic Anhydrase IX (CA IX): Acid-Base Regulator and Driver of Tumorigenesis

Carbonic anhydrase IX (CA IX) is a transmembrane, hypoxia-induced zinc metalloenzyme that converts carbon dioxide to bicarbonate and protons...
Newsletter

A Rising StAR in Cancer Research

Steroidogenic acute regulatory protein 1 (StAR/StARD1) mediates the rate-limiting step in steroidogenesis...
Newsletter

NEK7: An Essential Regulator of NLRP3 Inflammasome Activation

NEK7: An Essential Regulator of NLRP3 Inflammasome Activation
Newsletter
Nuclear PD-L1 Mediates Pyroptosis in Cancer Cells

Nuclear PD-L1 Mediates Pyroptosis in Cancer Cells

Nuclear PD-L1 Mediates Pyroptosis in Cancer Cells
Newsletter

Lateral Flow Assay for Influenza & SARS-CoV-2 Viruses Detection

Influenza A & B Virus Antibodies (IVD grade)
Newsletter
New Therapeutic Paradigm for Cancers with Activated NRF2

New Therapeutic Paradigm for Cancers with Activated NRF2

New Therapeutic Paradigm for Cancers with Activated NRF2
Newsletter
GeneTex Launches Novel Recombinant RAS (G12D Mutant) Antibody [HL10]

GeneTex Launches Novel Recombinant RAS (G12D Mutant) Antibody [HL10]

GeneTex's RAS (G12D mutant) recombinant antibody is suitable for IHC staining and WB.
Newsletter

A Cancer Immunotherapy Holy Grail?

A Cancer Immunotherapy Holy Grail?