GeneTex
  • Country / Location Selection

United States (US)
Tumor Suppressor Proteins

Tumor Suppressor Proteins

Tumor Suppressor Proteins

Tumor suppressor gene products, or tumor suppressor proteins, act as barriers to block cells from proceeding down the path to cancer. In contrast to the protein products of proto-oncogenes, some tumor suppressor proteins act to restrain abnormal cell proliferation. Others promote cell death pathways or function in DNA repair. While mutated proto-oncogenes behave in a dominant fashion, tumor suppressor genes are generally recessive, thus requiring that both be inactivated or otherwise compromised in order for cancers to occur. Well-described examples of tumor suppressor proteins include RB, p53, APC and CDKN2A/p14 ARF.

Highlighted Products
Citation Support KOKD Validation IP/MS Analysis Orthogonal Validation Protein Overexpression

 

p53 antibody
(GTX70214)

p53 antibody
(GTX70214)

Rb antibody
(GTX100545)

Rb antibody
(GTX100545)

CDKN2A / p14ARF antibody (GTX129902)

CDKN2A / p14ARF antibody (GTX129902)

BRCA1 antibody
(GTX70111)

BRCA1 antibody
(GTX70111)

BRG1 antibody 
(GTX633391)

BRG1 antibody 
(GTX633391)

SMAD2 antibody
(GTX111131)

SMAD2 antibody
(GTX111131)

Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
Pathways

Wnt Pathway

Wnt proteins are secreted morphogens that are required for various developmental processes.
Literature
Cancer Signaling

Poster - Cancer Signaling

Download the latest version of GeneTex's cancer signaling poster
Literature

Flyer - RNA-binding Proteins

Download the latest version of GeneTex's RNA-binding proteins flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature

Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research
Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
Literature
Cancer Signaling

Poster - Cancer Signaling

Download the latest version of GeneTex's cancer signaling poster
Literature

Flyer - RNA-binding Proteins

Download the latest version of GeneTex's RNA-binding proteins flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature

Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research